The Position

At Maze Therapeutics, we're on a mission to make a difference in the lives of people affected by common and rare diseases. If you're looking for a role where you can be hands-on in the execution of global clinical trials and directly contribute to advancing treatments for patients, this could be the perfect opportunity for you.

As a Clinical Trial Specialist, you'll play a key role in supporting our Clinical Operations team as we deliver an exciting and diverse pipeline of precision medicines. You'll collaborate closely with internal teams, CROs, and vendors to ensure the smooth execution of our clinical studies. This role is ideal for someone who enjoys problem-solving, thrives in a fast-paced environment, and is eager to take ownership of critical trial activities such as vendor and site management. This role will be supporting the MZE782 program for Chronic Kidney Disease.

This position reports to the Senior Clinical Trial Manager.

The Impact You'll Have

You'll be a critical part of our clinical team, ensuring our trials are executed with precision, efficiency, and the highest standards of quality. Your contributions will include:

Driving Study Execution: Support the Clinical Operations Study Leads to oversee and monitor the conduct of our clinical studies, monitoring progress, identifying trends or issues, and collaborating with Study Leads to implement corrective actions when necessary.
Site & Vendor Oversight: Support site management oversight to ensure CRO activities align with the Monitoring Plan and facilitating protocol deviation discussions for quick resolution.
Ensuring compliance & Best Practices: Ensure that all clinical trial activities adhere to ICH/GCP Guidelines, study protocols, and Maze SOPs.
Supporting Key Study Materials: Assist in the design and development of study documents, including protocols, informed consent forms (ICFs), amendments, and content creation for study materials.
Collaboration & Leadership: Attend and contribute to vendor meetings, lead resolution of study-related issues, and foster a culture of continuous process improvement with CROs and other external partners
Tracking & Documentation: Develop study trackers and tools to best support study conduct and track study metrics and deliverables. Oversee Trial Master File (TMF) activities, ensuring proper documentation, metric tracking and reconciliation efforts as needed. Manage process for submitting and executing clinical contracts, as appropriate.
Sample & Data Management: Work with study team to coordinate sample shipments, sample analysis, and data reconciliation efforts.
Cross-Functional Collaboration: Serve as a point of contact for study-related inquiries and provide high-level administration, coordination, and organizational support to the Clinical Operations team.

What We're Looking For

We're looking for someone who's not just checking the boxes but is truly passionate about executing high quality clinical trials to the highest of standards. You might be a great fit if you have:

A strong clinical trial and/or industry background: Bachelor's degree with 2+ years of experience in clinical trials – either at an academic institution or within a biotech/pharmaceutical environment.
A systematic and problem-solving mindset: You enjoy solving complex challenges and thinking critically to improve processes.
Exceptional organizational skills: You can manage multiple priorities, stay detail-oriented, and keep trials on track.
A proactive and collaborative approach: You're a strong team player who takes initiative and builds meaningful relationships with internal and external partners.
Hands-on experience with trial systems: Familiarity with clinical trial databases such as Medidata Rave, Veeva, or similar platforms.
Flexibility and adaptability: You're comfortable working in a fast-paced, evolving environment and willing to roll up your sleeves to perform a broad range of clinical trial related tasks as needed.
Learning agility: Ability to rapidly acquire, apply, and adapt knowledge, skills, and insights in dynamic and unfamiliar situations.
Willingness to travel: Up to 10-15% travel, with the possibility of more based on project needs.as necessary, consistent with project needs.
Strong computer proficiency (Microsoft Office Suite- Word, Excel, Outlook).

This role follows a hybrid schedule, with an expectation to be onsite at our South San Francisco headquarters at least two days per week.

About Maze Therapeutics

Maze Therapeutics is a clinical-stage biopharmaceutical company harnessing the power of human genetics to develop novel, small molecule precision medicines for patients living with renal, cardiovascular and related metabolic diseases, including obesity. The company is advancing a pipeline using its Compass platform, which allows it to identify and characterize genetic variants in disease and then link those variants to the biological pathways that drive disease in specific patient groups through a process it refers to as variant functionalization. The company's pipeline is led by two wholly owned lead programs, MZE829 and MZE782, each of which represents a novel precision medicine-based approach for chronic kidney disease. Maze is based in South San Francisco.

Our People

Maze is comprised of a team of passionate and creative professionals committed to discovering and delivering transformative medicines to patients suffering from both rare and common genetic diseases. We are fostering a culture that encourages vision, initiative and the development of talent. Our supportive work environment inspires creative thinking and freedom of expression, resulting in a stimulating atmosphere where people enjoy coming to work. While we have a passion for advanced science and pride ourselves on excellence in execution, ultimately, everything we do is about patients.

Our Core Values

Further Together – Our path is paved with challenges, but with resilience and a team-first mentality, we'll achieve our mission.

Impact Obsessed – We embrace the bold, take calculated risks, and learn from our mistakes to improve the lives of others.

Stand True – Our integrity is foundational; it guides us no matter the obstacle.

The expected annual salary range for employees located in the San Francisco Bay Area is $114,000 - $140,000. Additionally, this position is eligible for an annual performance bonus.

Maze performs position-based compensation benchmarking to industry market data to ensure we pay competitive wages. Determination of starting salary will depend upon a variety of job-related factors, which may include professional experience, skills, and job location. The expected salary range for this role may be modified in the future.

Maze offers a robust benefits package to our eligible employees including competitive medical, dental, and vision insurance, mental health offerings, equity incentive plan, 401(k) program with employer match and a generous holiday and PTO policy.

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